Acute liver injury.
نویسنده
چکیده
During metabolism in the liver the concentration of a drug or its metabolic products may be locally increased. This provides a theoretical basis for the large and ever-increasing number of reports of acute liver damage following drug therapy. If a drug or its metabolic product is a cellular poison we may expect a direct hepatotoxic reaction with a constant relationship to the level of drug in the serum and consequently with a relationship to the dose, ie, predictable liver injury (Scheuer, 1973).
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ورودعنوان ژورنال:
- Journal of clinical pathology. Supplement
دوره 9 شماره
صفحات -
تاریخ انتشار 1975